All of us know that heart attack is one of the most common causes of death in the world, especially in India. Stroke is another devastating malady which affects a person’s brain, and because of which a person dies or is afflicted with long term morbidities. Both the diseases are deadly, hence it’s important to prevent them. Here prevention is of two types – primary and secondary.
Those who are already having cardiovascular heart diseases or failure stand a high chance of dying early. Similar is the case with stroke. Those afflicted with stroke too have a high rate of fatality–these come under secondary prevention.
Primary prevention is for those who have never had a heart attack, nor have had any heart related issues, or have never had any signs or symptoms of stroke after they are 30 or 40. For such people there is good news, for they can now successfully prevent heart attacks or stroke! Recently, the American Heart Association announced the results of a trial which says aspirin when added to polypill (statin and ACEI in one cap) can prevent heart attacks and stroke to a great extent. Many Indian patients participated in the study.
According to the findings in the TIPS-3 study presented on Nov. 13, 2020, people who never have had any kind of heart diseases or stroke, can reduce the possibility of a heart attack by taking a polypill with aspirin every day. Based on these findings, “aspirin should be prescribed with a polypill as a primary prevention for patients at intermediate risk of heart disease,” said Dr. Salim Yusuf, one of the researchers who also presented a paper on the aspirin aspect of the study (TIPS + ASA). “Our study results provide important data regarding the role of polypill in preventing the development of heart disease.” The study says that heart attacks, strokes and other cardiovascular incidents can be reduced through the use of a pollypill, which combines blood pressure and lipid-lowering medications, taken with an aspirin. The primary analysis on this is now over. 
There have been many earlier studies in this regard with mixed results, some suggesting the benefits of aspirin, while others remained unclear. Now, as per the latest findings, polypill can be of great help to those above 45-50 with hypertension or diabetes or any other risk factor. This would also reduce the pill-burden (number of pills taken by a person) from many to one, making it easier for people to stick to their treatment regimen. And this, in turn, will benefit people prone to heart diseases, especially in India where the risk is higher than that of Europe or America. Also, this game-changer will be more useful if the person involved is physically active, sticks to a healthy diet and is a non-smoker.
In a statement, Dr. Yusuf Kumble,  Chief Interventional Cardiologist and managing director of Indiana Hospital and Heart Institute, Mangaluru, said, “This new development will have a big impact in India where aspirin is easily available at a very low cost, and thus we can prevent heart attacks by introducing the polypill model in primary health centres and other private hospitals.”
(Compiled by Indiana Marketing Team)